How much is a flight from Mexico City to Santa Cruz de la Sierra?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Mexico City and Santa Cruz.

Pick a travel date to see today’s available fares.

Fares change often — checking several times throughout the week can make a big difference. Booking in advance often means access to lower prices for the Mexico City - Santa Cruz de la Sierra route.

Which airports serve Mexico City and Santa Cruz?

When planning a trip of about 5692 km, it's a good idea to check flights from surrounding airports too.

• Airports in Mexico City: International is also an option alongside Mexico City - International.
• Airports in Santa Cruz: Another nearby option is Santa Cruz.

The closest airport isn’t always the cheapest — it’s worth checking the alternatives too. In some cities, smaller airports offer lower fares than the main ones.

Customize your flight from Mexico City to Santa Cruz de la Sierra

Jetcost allows you to filter by travel dates, duration, layovers, carriers, and booking providers. You’ll find direct and connecting flights, one-way or round-trip, from the best airlines and travel agencies.

Other popular destinations

Thinking about Bolivia? You might also consider: Cochabamba, La Paz, Santa Cruz, Sucre, Tarija.

You can sort results by price, duration, or departure time to find the best option for you. When available, results always include both low-cost and traditional airlines.